Airport officials have announced that roundtrip service to both cities will be available Mondays, Wednesdays and Saturdays. There will also be Chicago flight on Tuesdays and an Indianapolis flight on Fridays.
Introductory one fares are $59 for the Indianapolis flights and $69 for the Chicago flights.
The new flights will be flown by ExpressJet Airlines and will be marketed as public charter flights by Branson AirExpress.
Branson attracts about 8 million visitors a year.